图书简介
The first interdisciplinary compilation of research on the biobehavioral basis of cancer-related symptoms, combining scientific input with patient, government and industry perspectives. With an expert editorial team led by an internationally-recognized leader in cancer pain assessment and treatment, this is essential reading for clinicians, oncologists, academic researchers and pharmaceutical companies.
Preface; Foreword; Part I. Introduction: 1. Introduction to Cancer Symptom Science Charles S. Cleeland, Adrian J. Dunn and Michael J. Fisch; 2. Researching the mechanisms underlying the symptoms of patients with cancer Adrian J. Dunn; 3. Cytokines, sickness behavior: a model for cancer symptoms Steven S. Zalcman, Randall T. Woodruff, Ruchika Mohla and Allan Siegal; Part II. Cancer Symptom Mechanisms and Models: Clinical and Basic Science: 4. The clinical science of cancer pain assessment and management Russell K. Portenoy and Victor T. Chang; 5. Pain: basic science: 5a. Mechanisms of disease-related pain in cancer: insights from the study of bone tumors Patrick W. Mantyh and Juan Miguel Jimenez Andrade; 5b. Neuropathic pain: basic science Patrick M. Dougherty and Haijun Zhang; 6. Cognitive dysfunction: is chemobrain real? Christina A. Meyers and Jeffrey S. Wefel; 7. Cognitive impairment: basic science Perry N. Fuchs, Jessica A. Boyette-Davis and Adrian J. Dunn; 8. Depression in cancer: pathophysiology at the mind-body interface Andrew H. Miller, Michael A. Burke and Charles L. Raison; 9. Depressive illness: basic science: 9a. Animal models of depressed mood and sickness behavior Adrian J. Dunn; 9b. From inflammation to sickness and depression: the cytokine connection Robert Dantzer and Keith W. Kelly; 10. Cancer-related fatigue: clinical science Xin Shelley Wang; 11. Developing translational animal models of cancer-related fatigue Mary W. Meagher; 12. Cancer anorexia/weight loss syndrome Aminah Jatoi and Nisha Lassi; 13. Appetite loss/cachexia: basic science Tristin D. Brisbois-Clarkson, Wendy V. Wismer and Vickie E. Baracos; 14. Sleep and its disorders: clinical science Sofia Ancoli-Israel and Lianqi Liu; 15. Sleep and its disorders Mark R. Opp and Luca Imeri; 16. Proteins and symptoms Bang-Ning Lee and James M. Reuben; 17. Genetic approaches to treating and preventing symptoms in patients with cancer Quiling Shi and Charles S. Cleeland; 18. Functional imaging of symptoms T. Dorina Papageorgiou, Edward F. Jackson and Javier O. Valenzuela; 19. High-dose therapy and posttransplantation symptom burden: striking a balance Sergio A. Giralt and Loretta A. Williams; Part III. Clinical Perspectives in Symptom Management and Research: 20. Promoting symptom research in cooperative groups Lynne I. Wagner and David Cella; 21. Practical aspects of symptom management in patients with cancer Richard T. Lee and Michael J. Fisch; Part IV. Symptom Measurement: 22. Symptom measurement by patient report Charles S. Cleeland and Tito R. Mendoza; 23. The economics of cancer-related symptoms: valuing supportive care interventions Lesley-Ann Miller and Jane C. Weeks; 24. Longitudinal models for symptoms Diane L. Fairclough; 25. Bayesian adaptive design: a new approach to test the effectiveness of symptom-reducing agents using patient-reported outcomes Valen E. Johnson and Tito R. Mendoza; Part V. Government and Industry Perspectives: 26. Promoting cancer symptom science research Ann O?Mara and Maria Sgambati; 27. Developing symptom management drugs Joanna M. Brell and Lori M. Minasian; 28. Cancer-related symptoms: issues for consideration in drug and therapeutic biological product label claims in the United States Jane A. Scott; 29. Symptom research: looking ahead Charles S. Cleeland, Adrian J. Dunn and Michael J. Fisch; Index.
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