Molecular Hydrogen in Health and Disease

Molecular Hydrogen in Health and Disease（Advances in Biochemistry in Health and Disease）

健康与疾病中的分子氢
生物化学

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作者

Jan Slezak Branislav Kura

出版社

Springer Berlin Heidelberg

出版时间

2024年01月25日

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ＩＳＢＮ

9783031473746

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页码

564

语种

英文

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Molecular hydrogen (H2) has emerged as a promising therapeutic and preventive medical gas. Hydrogen gas has garnered significant attention in recent years due to its remarkable antioxidant and anti-inflammatory properties. H2 exhibits exceptional pharmacokinetics, swiftly traversing cellular biomembranes to access subcellular organelles indirectly regulating hormones and cytokines through various signal transduction pathways. H2 has the potential to address a wide range of issues, including clinical medical treatment in the areas of healthcare: myocardial ischemia, heart failure, cardiac arrest, metabolic syndrome, advanced-stage cancer, inflammatory diseases, Alzheimer’s dementia, aging-related disorders, sports activities, and even beauty, agriculture, etc.Selected world-known authors in the field provide readers with a comprehensive overview of molecular hydrogen’s remarkable effects and its physical, chemical, and therapeutic properties and potential in biomedical applications. This contributed volume fills the current gap in information and is intended for everyone who wants to be better informed about the wide possibilities of using molecular hydrogen. However, it is mainly intended for use by medical students, physiologists, pharmacologists, physicians, and other healthcare personnel who can use molecular hydrogen to improve the health of everyone who needs it.

Hydrogen: From Stars to Fuel to Medicine.- An exploration of the direct biological targets of molecular hydrogen.- Prospects of hydrogen medicine based on its protective effects on mitochondrial function.- Molecular hydrogen: A new treatment strategy of mitochondrial disorders.- Autonomic cardiac regulation in response to exercise and molecular hydrogen administration in well-trained athletes.- The Clinical Use of Hydrogen as a Medical Treatment.- Homeostatic and endocrine response underlying protective effects by molecular hydrogen.- Radiation-induced heart disease: potential role for molecular hydrogen.- Short-lasting supplementation with molecular hydrogen and vitamin E upregulates myocardial connexin-43 in irradiated and non-irradiated rat heart.- Molecular hydrogen: a new protective tool against radiation-induced toxicity.- Role of Matrix Metalloproteinases in Effects of Molecular Hydrogen.- Perioperative mitigation of oxidative stress with molecular hydrogen during simulated heart transplantation in pigs.- Application of Hydrogen in Hemodialysis: A brief review with emphasis on the quantification of dissolved H2.- Hydrogen as a potential therapeutic approach in the treatment of cancer: from bench to bedside.- The Role of the Smallest Molecule Hydrogen Overcoming Ageing-Related Disease.- Dihydrogen and Hepatic Function: Systematic Review and Meta-Analysis.- Hydrogen-rich water using as a modulator of gut microbiota and managing the inflammatory bowel diseases.- Effects of Molecular Hydrogen in the Pathophysiology and Management of Metabolic and Non-communicable Diseases.- Consumption of Hydrogen-Treated Foods Provides Nutritional and Health Benefits.- Differential effects of carbohydrates on the generation of hydrogen and methane in low- and high-methane-producing rats.- Natural Biomolecules, Plant Extracts and Molecular Hydrogen – New Antioxidant Alternatives in the Management of Male Infertility.- Comparison of free-radical scavenging activity of various sources of molecular hydrogen.- Development of a preclinical tool for measuring percutaneous transfer of dihydrogen, with a view to optimizing medical devices adapted to focal therapies in dermatology.- Intraosseous Administration of Molecular Hydrogen: A Novel Technique – From Molecular Effects To Tissue Regeneration.- Perspective of nanomaterials and nanomedicine procedures in molecular hydrogen therapy.- The emergence, development, and future mission of hydrogen medicine and biology.

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