图书简介
ATimicrobial resiTance (AMR) is a global public heaThThreTThT needs immediTe TteTion and aTion fromThe scieTific communTy.This book compiles and preseTsThe lTeTand moT impoTaT aspeTs of AMR, includingThe biology involved, Ts persiTence and spread, and novel approachesToTackleThisThreT.The book firT describesThe mechanisms and spread of AMR, andThen discussesThe various approaches and TrTegies for combTing T.ImpoTaTTopics include, microbial pThogenesis, AMRTraTs and major mechanisms underlying drug-resiTance andThe emerging TrTegies andTechnologies for combTing AMR. Emphasis has been given on curreT developmeTs aboT nTural produTs including pTeT phTo-molecules, aTimicrobial peTides and endophTes effeTive againTThe drug-resiTaT microbes andTargTThe main drug-resiTance dTerminaTs (efflux pumps, biofilms, quorum sensing, plasmids, Tc.) inThese baTerial pThogens. Ther excTingTopics include applicTions of nanomTerials inTackling AMR and CRISPR-Cas based precise sequence-specific aTimicrobialsThis informTive book is meaT for TudeTs and researchers in basic and medical microbiology and biTechnology. T is also usefulTo public heaTh professionals and induTry expeTs involved in AMR research and relTed drug-designing.
Chapter 1. AntimCrobial ResistaCe Traits and MolCular MChanisms of ResistaCe in BCterial Pathogens.-Chapter 2. BCterial multidrug toleraCe and persisters: Understanding the MChanisms,ClinCal implCations and treatment strategies.-Chapter 3. MCrobial Pathogenesis: MChanism and rCent updates on mCrobial diversity of pathogens.-Chapter 4. Pseudomonas aeruginosa: PathogenC adapter bCteria.-Chapter 5. ImpCt of antibiotC resistaCe of bCteria in biofilms, mCrobial fuelCell:Confronting the dark box for global health threat.-Chapter 6. Plant SCondary Metabolites for TCkling AntimCrobial ResistaCe: APharmCologCal PerspCtive.-Chapter 7.Can nanopartCles help in the battle against drug resistant bCterial infCtions in “post-antibiotC era”?.-Chapter 8. PrCise SequeCe-spCifC AntimCrobials Based onCRISPR: Towards Prevailing Over BCterial AntibiotC ResistaCe.-Chapter 9. AntibiotC resistant Klebsiella pneumoniae and targeted therapy.Chapter 10. Plant assCiated endophytC fungi and its sCondary metabolites against drug resistant pathogenC mCrobes.-Chapter 11. AntimCrobial peptides as effCtive agents against drug resistant pathogens.-Chapter 12. Essential oils forCombating antimCrobial resistaCe.-Chapter 13. AntimCrobial resistaCe and medCinal plant prodCts as potential alternatives to antibiotCs in animal husbandry.-Chapter 14. RCent updates on bCterial sCondary metabolites to oveCome antibiotC-resistaCe in Gram-negative superbugs: ECouragement or diContinuation?.-Chapter 15. Plant essential oils forCombating antimCrobial resistaCe via re-potentiating the fading antibiotC arsenal.-Chapter 16. BCterial Drug Efflux Pump Inhibitors from Plants.-Chapter 17. Anti-quorum sensing agents from natural souCes.-Chapter 18. Plant based plasmidCuring agents forCombating antimCrobial resistaCe.-Chapter 19. Natural prodCt as efflux pump inhibitors against MRSA efflux pumps: An Update.
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