Peroxiporins

图书简介

To produce energy, aerobic organisms transform oxygen molecules into water. This reductive mechanism yields toxic radical intermediates, collectively known as reactive oxygen species (ROS). Paradoxically, these physiological processes entail the production of potentially damaging species. Evolution has turned this apparent disadvantage into an opportunity for transmitting information. As a result, redox signaling within the cell is an efficient exquisitely organized process. A key element for its regulation is the physical separation of sources and targets into different cell compartments. Peroxiporins, H2O2 transporting proteins spanning biological membranes, distribute the signal from emitters to receptors. Thus, these channels are strategically situated in the thin line between life and death, guaranteeing adequate but safe signaling.Key Features:- Provides a brief history of the discovery and characterization of peroxiporins- Reviews key findings on hydrogen peroxide transport across biological membranes- Discusses the cartography of redox signaling in crowded cells- Includes lavish illustrations and comprehensive images to facilitate teaching- Highlights recent findings, outstanding controversies and open questions

Chapter 1-Role of the cellular hydrogen peroxide landscape profile in redox signaling Helmut Sies Chapter 2-How gradients and microdomains determine H2O2 redox signaling Fernando Antunesa, Armindo Salvador Chapter 3-Diffusion and transport of peroxynitrite across cell membranes Matías N. Möllera, Karina Allevac, Ari Zeidab, Rafael Radib Chapter 4-Hydrogen peroxide as a substrate for aquaporins from a structure-function perspective Eric Beitz Chapter 5-Use of genetically encoded reporters to quantify intracellular H2O2 levels in eukaryotic cells Laura de Cubasa, Fernando Antunesb, Olga Lyublinskayac, and Elena Hidalgoa Chapter 6-H2O2/ROS production, consumption and transport across organelles Tasuku Konno, Cécile Crapart, Edward Avezov Chapter 7-The Mystery behind Hydrogen Peroxide Permeation across the Peroxisomal Membrane Cláudio F. Costaa, Celien Lismont, Marco Anteghini, Iulia Revenco, Hongli Li, Marc Fransen Chapter 8-Role of mammalian aquaporin (AQP) inside the cell: An update. Kenichi Ishibashi, Yoshiyuki Morishita, Yasuko Tanaka-Mochizuki Chapter 9-Peroxiporins in plant-microbial interactions Barbara Ludwig Navarro, Kathrin Blumenstein, Daniela Elisabeth Nordzieke Chapter 10-Role of peroxiporins in plant stress signaling and development Stephanie Frohn, Bernd Dreyer, Romy Schmidt-Schippers, Jos H.M. Schippers Chapter 11-Evolution and function of peroxiporins in piscine spermatozoa Joan Cerdà, F

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Peroxiporins（Oxidative Stress and Disease） 过氧化物蛋白酶：细胞内与细胞间的氧化还原信号介质 细胞生物学

Peroxiporins（Oxidative Stress and Disease）

过氧化物蛋白酶：细胞内与细胞间的氧化还原信号介质
细胞生物学