Prototype of a Biomimetic Multi-Spiked Connecting Scaffold for a New Generation of Resurfacing Endoprostheses

图书简介

The monograph comprehensively presents the research on the prototype of the biomimetic Multi-Spiked Connecting Scaffold (MSC-Scaffold) for cementless fixation of the components of a new generation of resurfacing arthroplasty (RA) endoprostheses. This research, carried out by a bioengineering-surgical team from three Polish universities, includes bioengineering design, rapid prototyping, manufacturing in selective laser melting, functionalization, surface modification, numerical studies, experimental in vitro studies, and pilot surgical experiments in an animal model.Features:•Presents the prototype of the multi-spiked connecting scaffold for a new generation of resurfacing endoprostheses of the knee and the hip.•Explains this prototype scaffold as the first worldwide design of the biomimetic fixation of components of diarthrodial joints resurfacing endoprostheses.•Insights into the entire process of bioengineering design and research on this novel way of resurfacing endoprostheses fixation.•Reviews main results of the scaffold prototyping and SLM manufacturing, structural and osteoconductive functionalization, and surface modification. •Reports experimental and numerical investigations of mechanical behavior of the scaffold-bone system, cell culture studies, and pilot surgical experiments in animal models.This book is

Chapter 1. Characteristics of contemporary hip resurfacing arthroplasty endoprostheses and their possible postoperative complications Chapter 2. Idea of entirely non-cemented implantation of the components of hip resurfacing arthroplasty endoprostheses with the multi-spiked connecting scaffold Chapter 3. Design, rapid prototyping and manufacturing of the biomimetic multi-spiked connecting scaffold prototype for non-cemented resurfacing endoprostheses Chapter 4. Structural and osteoconductive functionalization of the interspike space of the prototype multi-spiked connecting scaffold Chapter 5. Formation of osteoinductive and osseointegrative properties of the bone-contacting surface of the multi-spiked connecting scaffold prototype by the electrochemical cathodic deposition of calcium phosphates Chapter 6. Research on the system of bone and the prototype multi-spiked connecting scaffold in order to design the structural and biomechanical properties of this system Chapter 7. Pilot study on the prototype multi-spiked connecting scaffold for non-cemented resurfacing endoprostheses in an animal model Chapter 8. Pilot microCT study of the impact of embedding the multi-spiked connecting scaffold on the density and compressive strength of the subchondral trabecular bone of femoral heads from patients with osteoarthritis Chapter 9. Summary, conclusions, and final remarks Appendixes

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Prototype of a Biomimetic Multi-Spiked Connecting Scaffold for a New Generation of Resurfacing Endoprostheses 用于新一代表面修复关节假体置换的仿生多刺连接支架的原型 生物医学工程学

Prototype of a Biomimetic Multi-Spiked Connecting Scaffold for a New Generation of Resurfacing Endoprostheses

用于新一代表面修复关节假体置换的仿生多刺连接支架的原型
生物医学工程学