图书简介
Now in paperback, the second edition of the Oxford Textbook of Critical Care addresses all aspects of adult intensive care management. Taking a unique problem-orientated approach, this is a key resource for clinical issues in the intensive care unit.
Section 1: ICU Organisation and Management: The Intensive Care Unit; Part 1.1: The Intensive Care Unit; 1 Design of the ICU; 2 Staffing models in the ICU; 3 Rapid response teams for the critically ill; 4 In-hospital transfer of the critically ill; 5 Pre- and inter-hospital transfer of the critically ill and injured; 6 Regional critical care delivery systems; 7 Integration of information technology in the ICU; 8 Multiple casualties and disaster response in critical care; 9 Management of pandemic critical illness; Part 1.2: Communication; 10 Effective teamwork in the ICU; 11 Communication with patients and families in the ICU; 12 Telemedicine in critical care; Part 1.3: Training; 13 Clinical skills in critical care; 14 Simulation training for critical care; 15 Leadership skills in the ICU; Part 1.4: Safety and Quality; 16 Patient safety in the ICU; 17 Policies, bundles and protocols in critical care; 18 Managing biohazards and environmental safety; 19 Managing ICU staff welfare, morale and burnout; Part 1.5: Governance; 20 ICU admission and discharge criteria; 21 Resource management and budgeting in critical care; 22 Costs and cost-effectiveness in critical care; Part 1.6: Research; 23 Evidence-based practice in critical care; 24 Research ethics in the ICU; Part 1.7: Medico-legal and ethical issues; 25 Informed consent in the ICU; 26 Patient rights in the ICU; 27 Medico-legal liability in critical care; Part 1.8: Critical Illness Risk Prediction; 28 The role and limitations of scoring systems; 29 Severity of illness scoring systems; 30 Organ failure scoring; 31 Genetic and molecular expression patterns in critical illness; Section 2: Pharmacotherapeutics; Part 2.1: Respiratory drugs; 32 Oxygen in critical illness; 33 Bronchodilators in critical illness; 34 Vasopressors in critical illness; 35 Vasodilators in critical illness; 36 Inotropic agents in critical illness; 37 Anti-anginal agents in critical illness; 38 Anti-arrhythmics in critical illness; 39 Pulmonary vasodilators in critical illness; Part 2.3: Gastrointestinal drugs; 40 Gastrointestinal motility drugs in critical illness; 41 Stress ulcer prophylaxis and treatment drugs in critical illness; Part 2.4: Nervous system drugs; 42 Sedatives and anti-anxiety agents in critical illness; 43 Analgesics in critical illness; 44 Antidepressants in critical illness; 45 Antiseizure agents in critical illness; 46 Inhalational anaesthetic agents in critical illness; 47 Muscle relaxants in critical illness; 48 Neuroprotective agents in critical illness; Part 2.5: Hormonal drugs; 49 Hormone therapies in critical illness; 50 Insulin and oral anti-hyperglycaemic agents in critical illness; Part 2.6: Haematological drugs; 51 Anticoagulants and antithrombotics in critical illness; 52 Haemostatic agents in critical illness; Part 2.7: Antimicrobial and immunological drugs; 53 Antimicrobial drugs in critical illness; 54 Steroids in critical illness; 55 Immunotherapy in critical illness; Part 2.8: Fluids and diuretics; 56 Colloids in critical illness; 57 Crystalloids in critical illness; 58 Diuretics in critical illness; Section 3: Resuscitation; Part 3.1: Respiratory management; 59 Airway management in cardiopulmonary resuscitation; 60 Artificial ventilation in cardiopulmonary resuscitation; Part 3.2: Circulatory management; 61 Pathophysiology and causes of cardiac arrest; 62 Cardiac massage and blood flow management during cardiac arrest; 63 Defibrillation and pacing during cardiac arrest; 64 Therapeutic strategies in managing cardiac arrest; 65 Post-cardiac arrest arrhythmias; 66 Management after resuscitation from cardiac arrest; 67 Ethical and end-of-life issues after cardiac arrest; Part 3.3: Fluid Management; 68 Physiology of body fluids; 69 Choice of resuscitation fluid; 70 Therapeutic goals of fluid resuscitation; Section 4: The Respiratory System; Part 4.1: Physiology; 71 Normal physiology of the respiratory system; Part 4.2: Respiratory monitoring; 72 Blood gas analysis in the critically ill; 73 Pulse oximetry and capnography in the ICU; 74 Respiratory system compliance and resistance in the critically ill; 75 Gas exchange principles in the critically ill; 76 Gas exchange assessment in the critically ill; 77 Respiratory muscle function in the critically ill; 78 Imaging the respiratory system in the critically ill; Part 4.3: Upper airway obstruction; 79 Upper airway obstruction in the critically ill; Part 4.4: Airway access; 80 Standard intubation in the ICU; 81 The difficult intubation in the ICU; 82 The surgical airway in the ICU; Part 4.5: Acute respiratory failure; 83 Dyspnoea in the critically ill; 84 Pulmonary mechanical dysfunction in the critically ill; 85 Hypoxaemia in the critically ill; 86 Hypercapnia in the critically ill; 87 Cardiovascular interactions in respiratory failure; Part 4.6: Ventilatory support; 88 Physiology of positive-pressure ventilation; 89 Respiratory support with continuous positive airways pressure; 90 Non-invasive positive-pressure ventilation; 91 Indications for mechanical ventilation; 92 Design and function of mechanical ventilators; 93 Setting rate, volume, and time in ventilatory support; 94 Respiratory support with positive end-expiratory pressure; 95 Volume-controlled mechanical ventilation; 96 Pressure-controlled mechanical ventilation; 97 Pressure support ventilation; 98 High-frequency ventilation and oscillation; 99 Prone positioning in the ICU; 100 Failure to ventilate in critical illness; 101 Ventilator trauma in the critically ill; Part 4.7: Weaning ventilatory support; 102 Assessment and technique of weaning; 103 Weaning failure in critical illness; Part 4.8: Extracorporeal support; 104 Extracorporeal respiratory and cardiac support techniques in the ICU; 105 Treating respiratory failure with extracorporeal support in the ICU; Part 4.9: Aspiration and inhalation; 106 Aspiration of gastric contents in the critically ill; 107 Inhalation injury in the ICU; Part 4.10: Acute respiratory distress syndrome; 108 Pathophysiology of acute respiratory distress syndrome; 109 Therapeutic strategy in acute respiratory distress syndrome; Part 4.11: Airflow limitation; 110 Pathophysiology and causes of airflow limitation; 111 Therapeutic approach to bronchospasm and asthma; 112 Therapeutic strategy in acute or chronic airflow limitation; Part 4.12: Respiratory acidosis and alkalosis; 113 Pathophysiology and therapeutic strategy of respiratory acidosis; 114 Pathophysiology and therapeutic strategy of respiratory alkalosis; Part 4.13: Pneumonia; 115 Pathophysiology of pneumonia; 116 Diagnosis and management of community-acquired pneumonia; 117 Diagnosis and management of nosocomial pneumonia; 118 Diagnosis and management of atypical pneumonia; Part 4.14: Atelectasis and sputum retention; 119 Pathophysiology and prevention of sputum retention; 120 Lung recruitment techniques in the ICU; 121 Chest physiotherapy and tracheobronchial suction in the ICU; 122 Toilet bronchoscopy in the ICU; Part 4.15: Pleural cavity disorders; 123 Pathophysiology of pleural cavity disorders; 124 Management of pneumothorax and bronchial fistulae; 125 Management of pleural effusion and haemothorax; Part 4.16: Hemoptysis; 126 Pathophysiology and causes of haemoptysis; 127 Therapeutic approach in haemoptysis; Section 5: The Cardiovascular System; Part 5.1: Physiology; 128 Normal physiology of the cardiovascular system; Part 5.2: Cardiovascular monitoring; 129 ECG monitoring in the ICU; 130 Arterial and venous cannulation in the ICU; 131 Blood pressure monitoring in the ICU; 132 Central venous pressure monitoring in the ICU; 133 Pulmonary artery catheterization in the ICU; 134 Mixed and central venous oxygen saturation monitoring in the ICU; 135 Right ventricular function in the ICU; 136 Cardiac output assessment in the ICU; 137 Oxygen transport in the critically ill; 138 Tissue perfusion monitoring in the ICU; 139 Lactate monitoring in the ICU; 140 Measurement of extravascular lung water in the ICU; 141 Doppler echocardiography in the ICU; 142 Monitoring the microcirculation in the ICU; 143 Imaging the cardiovascular system in the ICU; Part 5.3: Acute chest pain and coronary syndromes; 144 Causes and diagnosis of chest pain; 145 Pathophysiology of coronary syndromes; 146 Diagnosis and management of non-STEMI coronary syndromes; 147 Diagnosis and management of ST-elevation myocardial infarction; Part 5.4: Aortic dissection; 148 Pathophysiology, diagnosis, and management of aortic dissection; Part 5.5: The hypotensive patient; 149 Pathophysiology of shock; 150 Diagnosis and management of shock in the ICU; Part 5.6: Cardiac failure; 151 Pathophysiology and causes of cardiac failure; 152 Therapeutic strategy in cardiac failure; 153 Intra-aortic balloon counterpulsation in the ICU; 154 Ventricular assist devices in the ICU; Part 5.7: Tachyarrhythmias; 155 Causes and diagnosis of tachyarrythmias; 156 Therapeutic strategy in tachyarrhythmias; Part 5.8: Bradyarrhythmias; 157 Causes, diagnosis and therapeutic strategy in bradyarrhythmias; Part 5.9: Valvular problems; 158 Causes and diagnosis of valvular problems; 159 Therapeutic strategy in valvular problems; Part 5.10: Endocarditis; 160 Pathophysiology and causes of endocarditis; 161 Prevention and treatment of endocarditis; Part 5.11: Severe hypertension; 162 Pathophysiology and causes of severe hypertension; 163 Management of severe hypertension in the ICU; Part 5.12: Severe capillary leak; 164 Pathophysiology of severe capillary leak; 165 Management of acute non-cardiogenic pulmonary oedema; Part 5.13: Pericardial tamponade; 166 Pathophysiology and causes of pericardial tamponade; 167 Management of pericardial tamponade; Part 5.14: Pulmonary hypertension; 168 Pathophysiology and causes of pulmonary hypertension; 169 Diagnosis and management of pulmonary hypertension; Part 5.15: Pulmonary embolus; 170 Pathophysiology and causes of pulmonary embolus; 171 Diagnosis and management of pulmonary embolus; Section 6: The Gastrointestinal System; Part 6.1: Physiology; 172 Normal physiology of the gastrointestinal system; 173 Normal physiology of the hepatic system; Part 6.2: Gastrointestinal monitoring; 174 Imaging the abdomen in the critically ill; 175 Hepatic function in the critically ill; Part 6.3: Gastrointestinal haemorrhage; 176 Pathophysiology and causes of upper gastrointestinal haemorrhage; 177 Diagnosis and management of upper gastrointestinal haemorrhage in the critically ill; 178 Diagnosis and management of variceal bleeding in the critically ill; 179 Pathophysiology and causes of lower gastrointestinal haemorrhage; 180 Diagnosis and management of lower gastrointestinal haemorrhage in the critically ill; Part 6.4: Disordered gastric motility; 181 Vomiting and large nasogastric aspirates in the critically ill; 182 Ileus and obstruction in the critically ill; 183 Diarrhoea and constipation in the critically ill; Part 6.5: The acute abdomen in the ICU; 184 Pathophysiology and management of raised intra-abdominal pressure in the critically ill; 185 Perforated viscus in the critically ill; 186 Ischaemic bowel in the critically ill; 187 Intra-abdominal sepsis in the critically ill; 188 Acute acalculous cholecystitis in the critically ill; 189 Management of the open abdomen and abdominal fistulae in the critically ill; Part 6.6: Pancreatitis; 190 Pathophysiology, diagnosis and assessment of acute pancreatitis; 191 Management of acute pancreatitis in the critically ill; Part 6.7: Jaundice; 192 Pathophysiology and causes of jaundice in the critically ill; 193 Management of jaundice in the critically ill; Part 6.8: Acute hepatic failure; 194 Pathophysiology and causes of acute hepatic failure; 195 Diagnosis and assessment of acute hepatic failure in the critically ill; 196 Management of acute hepatic failure in the critically ill; 197 The effect of acute hepatic failure on drug handling in the critically ill; 198 Extracorporeal liver support devices in the ICU; Part 6.9: Acute on chronic hepatic failure; 199 199: Pathophysiology, diagnosis, assessment of acute or chronic hepatic failure; 200 Management of acute or chronic hepatic failure in the critically ill; Section 7: Nutrition; Part 7.1: Physiology; 201 Normal physiology of nutrition; 202 The metabolic and nutritional response to critical illness; Part 7.2: Nutritional failure; 203 Pathophysiology of nutritional failure in the critically ill; 204 Assessing nutritional status in the ICU; 205 Indirect calorimetry in the ICU; 206 Enteral nutrition in the ICU; 207 Parenteral nutrition in the ICU; Section 8: The Renal System; Part 8.1: Physiology; 208 Normal physiology of the renal system; Part 8.2: Renal monitoring and risk prediction; 209 Monitoring renal function in the critically ill; 210 Imaging the urinary tract in the critically ill; Part 8.3: Oliguria and acute kidney injury; 211 Pathophysiology of oliguria and acute kidney injury; 212 Diagnosis of oliguria and acute kidney injury; 213 Management of oliguria and acute kidney injury in the critically ill; Part 8.4: Renal replacement techniques; 214 Continuous haemofiltration techniques in the critically ill; 215 Haemodialysis in the critically ill; 216 Peritoneal dialysis in the critically ill; Part 8.5: Established renal failure; 217 The effect of renal failure on drug handling in critical illness; 218 The effect of chronic renal failure on critical illness; Section 9: The Neurological System; Part 9.1: Anatomy and physiology; 219 Normal anatomy and physiology of the brain; 220 Normal anatomy and physiology of the spinal cord and peripheral nerves; Part 9.2: Neurological monitoring; 221 Electroencephalogram monitoring in the critically ill; 222 Cerebral bloodflow and perfusion monitoring in the critically ill; 223 Intracranial pressure monitoring in the ICU; 224 Imaging the central nervous system in the critically ill; Part 9.3: Sleep disturbance; 225 Pathophysiology and therapeutic strategy for sleep disturbance in the ICU; Part 9.4: Agitation, confusion and delirium; 226 Causes and epidemiology of agitation, confusion and delirium in the ICU; 227 Assessment and therapeutic strategy for agitation, confusion and delirium in the ICU; Part 9.5: The unconscious patient; 228 Causes and diagnosis of unconsciousness; 229 Management of unconsciousness in the ICU; 230 Non-pharmacological neuroprotection in the ICU; Part 9.6: Seizures; 231 Pathophysiology and causes of seizures; 232 Assessment and management of seizures in the critically ill; Part 9.7: Intracranial hypertension; 233 Causes and management of intracranial hypertension; Part 9.8: Stroke; 234 Epidemiology of stroke; 235 Diagnosis and assessment of stroke; 236 Management of ischaemic stroke; 237 Management of parenchymal haemorrhage; Part 9.9: Non-traumatic subarachnoid haemorrhage; 238 Epidemiology, diagnosis, and assessment on non-traumatic subarachnoid haemorrhage; 239 Management of non-traumatic subarachnoid haemorrhage in the critically ill; Part 9.10: Meningitis and encephalitis; 240 Epidemiology, diagnosis and assessment of meningitis and encephalitis; 241 Management of meningitis and encephalitis in the critically ill; Part 9.11: Non-traumatic spinal injury; 242 Pathophysiology, causes, and management of non-traumatic spinal injury; Part 9.12: Neuromuscular syndromes; 243 Epidemiology, diagnosis, and assessment of neuromuscular syndromes; 244 Diagnosis, assessment, and management of myasthenia gravis and paramyasthenic syndromes; 245 Diagnosis, assessment, and management of tetanus, rabies and botulism; 246 Diagnosis, assessment, and management of Guillain-Barre syndrome; 247 Diagnosis, assessment, and management of hyperthermic crises; 248 Diagnosis, assessment, and management of ICU acquired weakness; Section 10: The Metabolic and Endocrine Systems; Part 10.1: Physiology; 249 Normal physiology of the endocrine system; Part 10.2: Electrolyte disturbance; 250 Disorders of sodium in the critically ill; 251 Disorders of potassium in the critically ill; 252 Disorders of magnesium in the critically ill; 253 Disorders of calcium in the critically ill; 254 Disorders of phosphate in the critically ill; Part 10.3: Metabolic acidosis and alkalosis; 255 Pathophysiology and causes of metabolic acidosis in the critically ill; 256 Management of metabolic acidosis in the critically ill; 257 Pathophysiology, causes, and management of metabolic alkalosis in the critically ill; Part 10.4: Blood glucose control; 258 Pathophysiology of glucose control; 259 Glycaemic control in critical illness; 260 Management of diabetic emergencies in the critically ill; Part 10.5: Endocrine disorders; 261 Pathophysiology and management of adrenal disorders in the critically ill; 262 Pathophysiology and management of pituitary disorders in the critically ill; 263 Pathophysiology and management of thyroid disorders in the critically ill; 264 Pathophysiology and management of functional endocrine tumours in the critically ill; Section 11: The Haematological System; Part 11.1: Laboratory monitoring; 265 The blood cells and blood count; 266 Coagulation monitoring; Part 11.2: Haematological therapies; 267 Blood product therapy in the ICU; 268 Apheresis in the ICU; Part 11.3: Disordered coagulation; 269 Pathophysiology of disordered coagulation; 270 Disseminated intravascular coagulation in the critically ill; 271 Prevention and management of thrombosis in the critically ill; 272 Thrombocytopenia in the critically ill; Part 11.4: Disorders of the blood cells; 273 Pathophysiology and management of anaemia in the critically ill; 274 Pathophysiology and management of neutropenia in the critically ill; 275 Sickle crisis in the critically ill; Section 12: The Skin and Connective Tissue; Part 12.1: Skin and connective tissue disorders; 276 Assessment and management of dermatological problems in the critically ill; 277 Vasculitis in the critically ill; 278 Rheumatoid arthritis in the critically ill; Part 12.2: Wound and pressure sore management; 279 Principles and prevention of pressure sores in the ICU; 280 Dressing techniques for wounds in the critically ill; Section 13: Infection; Part 13.1: Diagnosis and surveillance; 281 Microbiological surveillance in the critically ill; 282 Novel biomarkers of infection in the critically ill; Part 13.2: Nosocomial infection; 283 Definition, epidemiology and general management of nosocomial infection; 284 Healthcare worker screening for nosocomial pathogens; 285 Environmental decontamination and isolation strategies in the ICU; 286 Antimicrobial selection policies in the ICU; 287 Oral, nasopharyngeal and gut decontamination in the ICU; 288 Diagnosis, prevention, and treatment of device-related infection in the ICU; 289 Antibiotic resistance in the ICU; Part 13.3: Infection in the immunocompromised; 290 Drug-induced depression of immunity in the critically ill; 291 HIV in the critically ill; Part 13.4: Tropical diseases; 292 Diagnosis and management of malaria in the ICU; 293 Diagnosis and management of viral haemorrhagic fevers in the ICU; 294 Other tropical diseases in the ICU; Part 13.5: Sepsis; 295 Assessment of sepsis in the critically ill; 296 Management of sepsis in the critically ill; 297 Pathophysiology of septic shock; 298 Management of septic shock in the critically ill; Section 14: Inflammation; Part 14.1: Physiology; 299 Innate immunity and the inflammatory cascade; Part 14.2: Organ-specific biomarkers; 300 Brain injury biomarkers in the critically ill; 301 Cardiac injury biomarkers in the critically ill; 302 Renal injury biomarkers in the critically ill; Part 14.3: Host response; 303 The host response to infection in the critically ill; 304 The host response to trauma and burns in the critically ill; 305 The host response to hypoxia in the critically ill; 306 Host-pathogen interactions in the critically ill; 307 Coagulation and the endothelium in acute injury in the critically ill; 308 Ischemia-reperfusion injury in the critically ill; 309 Repair and
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