图书简介
Now in a revised and expanded third edition, this case-based guide emphasizes the latest investigative advances in both imaging and molecular diagnostics and new treatment approaches for a wide variety of common and complex endocrine conditions. Utilizing unique clinical case histories, each main endocrine condition and disorder is curated by a senior Section Editor with an introduction to his or her area covering both physiology and pathophysiology. This introductory chapter is followed by a number of case histories written by invited experts and designed to cover the important relevant pathophysiology, following a consistent chapter format for ease of use, including bulleted objectives, case presentations, review of the diagnosis, lessons learned, and 3-5 multiple-choice review questions. Section headings include the pituitary, thyroid (overactivity, underactivity and cancer) and parathyroid, adrenal disorders, metabolic bone disease, type 2 diabetes, lipid abnormalities, obesity, and pregnancy. Topics new to this edition include PCOS, transgender medicine and the endocrine effects of viral infections.With a focus on covering major parts of the APDEM curriculum, A Case-Based Guide to Clinical Endocrinology remains a tremendous resource for junior and veteran clinicians alike.
Part I. Pituitary Disorders.- Introduction to Pituitary Disorders.- Pituitary Tumor Behavior and Disease Severity in Patients with Acromegaly.- Abrupt Weight Gain, Hypertension and Severe Hypokalemia in a Young Male.- Dopamine Agonist-Induced Impulse Control Disorders.- Part II. Thyroid Overactivity.- Introduction to Thyroid Overactivity.- Immunoglobin G4 and Grave’s Orbitopathy.- Subclinical Hyperthyroidism: Case Report and Review of the Literature.- A Case of Gestational Thyrotoxicosis.- Part III. Thyroid Underactivity.- Introduction to Thyroid Underactivity.- Managing Hypothyroidism: Increasing Levothyroxine Requirements.- Gastrointestinal Disease and Levothyroxine Absorption.- Drug-Induced Central Hypothyroidism.- Part IV. Thyroid Cancer.- Introduction to Thyroid Cancer.- Papillary Thyroid Cancer.- Anaplastic Thyroid Carcinoma.- Medullary Thyroid Carcinoma.- Part V. Adrenal Disorders.- Introduction to Adrenal Disorders.- Adrenal Incidentalomas and Autonomous Cortisol Secretion.- Pheochromocytoma.- Ectopic ACTH Syndrome.- Part VI. Primary Hyperparathyroidism.- Introduction to Primary Hyperparathyroidism.- Cinacalcet Use in Primary Hyperparathyroidism.- A Case of Apparently Sporadic Primary Hyperparathyroidism Carrying a Germline Mutation of CDC73 Gene.- Challenges in the Preoperative Localization of Hyperfunctioning Parathyroid Tissue in a Patient with Primary Hyperparathyroidism.- Part VII. Metabolic Bone Diseases.- Introduction to Metabolic Bone Diseases.- Type 2 Diabetes and Bone.- Hypercalcemia and High Bone Mineral Density.- Rare Presentation of Severe Pediatric Rickets.- Part VIII. Endocrine Disorders in Men.- Introduction to Endocrine Disorders in Men.- Adult Onset Hypogonadism.- Congenital Hypogonadotropic Hypogonadism.- Klinefelter Syndrome.- Part IX. Endocrine Disorders in Pregnancy.- Introduction to Endocrine Disorders in Pregnancy.- Prolactinoma in Pregnancy.- Adrenal Insufficiency in Pregnancy.- Pheochromocytoma in Pregnancy.- Diagnosis and Management of Thyroid Cancer in Pregnant Women.- Part X. Type 2 Diabetes Mellitus.- Introduction to Type 2 Diabetes Mellitus.- Initial Diagnosis and Management of Type 2 Diabetes Mellitus.- Outpatient Management of Type 2 Diabetes Mellitus.- Inpatient Management of Type 2 Diabetes Mellitus.- Part XI. Lipid Abnormalities.- Introduction to Lipid Abnormalities.- A Case of Heterozygous Familial Hypercholesterolemia: Success of Long-term Management.- A 53 Year Old Man with Severe Combined Hyperlipidemia and Multiple Medication Sensitivities.- Familial Partial Lipodystrophy Presenting as Extreme Hypertriglyceridemia and Acute Pancreatitis.- Part XII. Obesity.- Introduction to Obesity.- Obesity Assessment and Management Using an Illustrative Case in Severe Mental Illness.- Obesity Management and Use of Very Low Energy Diets.- Obesity Case Management: Bariatric Surgery.- Part XIII. Polycystic Ovary Syndrome.- Introduction to Polycystic Ovary Syndrome.- PCOS and Hirsuties.- PCOS and Reproduction.- PCOS and Insulin Resistance.- PCOS and the Metabolic Syndrome.- Part XIV. Transgender Medicine.- Introduction to Transgender Medicine.- Trans-Masculine Therapy.- Peri-operative Estrogen Considerations for Transgender Women Undergoing Vaginoplasty.- Feminizing Gender-Affirming Hormone Therapy: Special Considerations for Older Adults.- Part XV. Endocrine Effects in Virus Infections.- Introduction to Endocrine Effects in Virus Infections.- Adrenal Function in HIV Infection.- HIV Infection and Lipodystrophy.- Endocrinopathies of SARS-CoV-2.
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