图书简介
With the start of 2020, the wrath of pandemic challenged the scientific community to develop more advanced drug delivery approaches for biomedical applications, endowing conventional drugs with additional therapeutic benefits and minimum side effects. Although significant advancements have been done in the field of drug delivery, there is a need to focus towards strategizing novel and improved drug delivery systems that should be convenient and cost-effective to the patients, and simultaneously they should also provide financial benefits to pharmaceutical companies. Controlled drug delivery technology offers ample opportunities and scope for improvising the therapeutic efficacy of drugs via optimizing the drug release rate and time. For this endeavour, smart nanomaterials have served as remarkable candidates for biomedical applications, owing to their ground-breaking properties and design. The development of such nanomaterials requires a broad knowledge related to their physio-chemical properties, molecular structure, mechanisms by which the nanomaterials interact with the cells, and methods by which drugs are released at the site of action. This knowledge must also be allied with the knowledge of signaling crosstalk mechanisms that are modulated by the nanomaterial-drugs composite. It can be anticipated that these emerging drug delivery technologies can facilitate the world to successfully encounter such pandemic outbursts in the future in a cost-effective and time-effective manner. The chapters in this book deal with the advanced technologies and approaches that can benefit advanced students, researchers, and industry experts in developing smart and intelligent nanomaterials for future biomedical applications, and development, manufacturing, and commercialization for controlled and targeted drug delivery.
Foreword.- Preface.- Introduction to active smart nanomaterials for biomedical applications.- Cancer cell sensing and therapy using affinity tag-conjugated gold nanoparticles.- Gold nanoparticles enlighten the future of cancer theranostics.- Recent advances in hydrogels smart drug delivery systems.- Carbon-based nanomaterials for biomedical applications.- A new era of cancer treatment: carbon nanotubes as drug delivery tools.- pH- and ion-sensitive materials for control drug delivery.- Thermo-responsive polymers and their application as smart biomaterias.- Redox-responsive polymers and their application in drug delivery systems.- Recent strategies to explore the biomedical applications of nanocellulose.- Tissue engineering using cellulose nanofibrils as Scaffold material.- Use of solidlipid nanoparticles to improve the oral bioavailability of poor soluble drugs.- Applications of dendrimers in drug delivery systems.- Liposomes for drug delivery: progress and problems.- Cubosome nanoparticles for enhanced delivery of anticancer drug.- Layer-by-Layer assemblies for cancer diagnosis and treatment.- Polymeric micelles for drug delivery.- Role of plant-based materials/gums in developing drug delivery systems.- Ethosomes: A novel tool for drug delivery through the skin.- Niosomes as nanoparticular drug carriers: fundamentals and recent applications.- Graphene oxide nanosheets used in photothermal therapy.- Metal doped carbon dots used in bio-imaging and cancer therapy.- Bibliography.- Glossary.- Index.
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