Nature’s Gift to Neuroscience

大自然给神经科学的礼物:悉尼·布伦纳与约翰·苏尔斯顿纪念论文

发育生物学,古生物学

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出  版 社
出版时间
2021年11月29日
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精装
ISBN
9781032145211
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页      码
352
开      本
280 x 210 mm (8.25 x 11)
语      种
英文
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图书简介
In the 1960s, Sydney Brenner proposed to use the nematode worm Caenorhabditis elegans to discover the control mechanisms of animal development and to reveal how a small number of neurons generate different behaviours, giving birth to a vibrant community, which uses this animal model for their studies. Brenner was aided in his aim by John Sulston, who mapped the C. elegans cell lineages – from a single cell to the multicellular adult – which transformed the field of developmental biology. As a tribute to these two men, this book captures the perspectives of some of the early pioneers of the worm community, from Martin Chalfie, Robert Waterston and Donald Moerman to Catherine Rankin, Antony Stretton and John White. It also includes contributions from subsequent generations of the community, who explore the development and function of the C. elegans nervous system. This book features how this animal has become one of the best models for elucidating the biology of different sensory modalities and their complex behavioural outputs or how this animal’s survival strategies have contributed to our understanding of aging and neurodegeneration. Thus, this volume documents the development of the C. elegans neuroscience field, from infancy to maturity. The chapters in this book were originally published as a special issue of the Journal of Neurogenetics.
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