X-Ray Fluorescence In Biological Sciences

生物科学中的 X 射线荧光:原理、仪器和应用 2V 套装

分析化学

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作      者
出  版 社
出版时间
2022年04月20日
装      帧
精装
ISBN
9781119645542
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页      码
688
开      本
16.83 x 24.45 cm.
语      种
英文
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图书简介
Application of XRF in Biological Sciences will extensively cover the broad application of XRF in biological sciences including chemical biology, clinical science and plant science, and the advances of the XRF imaging technique in these fields. Particularly, the focus will be towards the understanding and investigating the intercellular structures and metal investigation in plant cells. X-ray fluorescence spectrometry (XRF) is a powerful tool for quantitative mapping of multi element allocations in biological cells. Technological developments of simple X-ray fluorescence spectrometry has resulted in a number of micro-analytical methods, such as energy dispersive X-ray fluorescence spectrometry (EDXRF), total reflection X-ray fluorescence spectrometry (TXRF), micro-proton induced X-ray emission (micro-PIXE), electron probe X-ray microanalysis (EPXMA), synchrotron-based X-ray fluorescence microscopy (SXRF, SRIXE, or micro-XRF) and secondary ion mass spectrometry (SIMS). These techniques have biological applications for different areas of study and are useful for the imaging of elemental distribution in the biological cells or section of tissues. XRF also has the special capabilities for trace element sensitivity, combined with the ability to provide information regarding the oxidation state and coordination of metal cations, so is ideally suited to study the intracellular distribution and speciation of trace elements, toxic heavy metals, therapeutic or diagnostic metal complexes, submicron elemental imaging of bacteria and protist cells, detecting the function of transition metals in neurodegenerative disorders. Thus, this book will provide the detailed information of XRF based techniques, including the protocol and practical approaches.
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