图书简介
This book summarizes rapid progress and innovation in transplantation and regenerative medicine - the merger of reconstructive plastic surgery and transplantation - called Vascularized Composite Allotransplantation. This merger includes face, hand, uteri, larynx, tongue, penis and trachea translplantations as well as other body part transplants using grafts derived from organ donors. These sorts of transplants are now performed more commonly. Cell therapies for immunomodulation are surrogates for immune responses after transplantation to non-invasive imaging of neuroregeneration for improving functional outcomes after transplant.
Contributors SECTION I: CELLULAR THERAPIES IN RECONSTRUCTIVE TRANSPLANTATION 1. Cell Therapies in Reconstructive Transplantation Curtis L. Cetrulo, Jr., Amalya S. Wilson, Abraham Matar, Radbeh Torabi, Mohammadreza S. Pakyari, Elise Lupon, Marion Goutard, and Alexandre G. Lellouch 2. Novel T-Regulatory Cell-Based Therapies in Vascularized Composite Allotransplantation: Translational Implications Yalcin Kulahci, Hulya Kapucu, James D. Fisher, and Steven R. Little SECTION II: UNIQUE CONSIDERATIONS AND EMERGING INDICATIONS IN RECONSTRUCTIVE TRANSPLANTATION 3. Invasive and Non-Invasive Surrogates for Chronic Rejection in Vascularized Composite Allotransplantation: Claims and Controversies Nicholas L. Robbins and Warren C. Breidenbach 4. Reperfusion Injury in Vascularized Composite Tissue Allografts: Impact on Graft Outcomes and Preventive Strategies Kagan Ozer 5. Pediatric Upper Extremity Vascularized Composite Allotransplantation: Progress and Insights Kevin J. Zuo, Anna Gold, Randi Zlotnik Shaul, Emily S. Ho, Gregory H. Borschel, and Ronald M. Zuker SECTION III: GRAFT MONITORING IN RECONSTRUCTIVE TRANSPLANTATION 6. Targeted Imaging and Therapeutic Technologies in Neuroregeneration Jelena M. Janjic, Mihaly Balogh, Sandeep Kumar Reddy Adena, Amanda Fitzpatrick, John A. Pollock, Vijay Gorantla, and Andrew J. Shepherd 7. Biomarkers and Surrogates of Acute Rejection in Vascularized Composite Allograft Transplantation Calum Honeyman, Helen Stark, Hayson Chenyu Wang, Joanna Hester, Henk Giele, and Fadi Issa SECTION IV: COMPOSITE TISSUE GRAFT MANIPULATION AND ENGINEERING 8. Bioengineering Composite Tissue Constructs: Concepts and Challenges Kavit Amin, David Leonard, Li Yenn Yong, Ralph Murphy, Roxaana Moscalu, Kristen Liggat, and Jason Wong 9. Advances in Biomaterials for Reconstructive Transplantation Ashish Dhayani and Praveen Kumar Vemula 10. Gene Editing Strategies for Immunomodulation: Translation from Cells to Vascularized Tissues Fatih Zor, Esra Goktas, and Vijay Gorantla Index
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