图书简介

Section 1: Historical; 1 JAW (Tony) Wildsmith: Local anaesthetic substitutes for cocaine; 2 Ben M. Thomas: Innovative concepts in pain management; 3 Sebastian Brandner and Brigitta Brandner: Explaining reflex sympathetic dystrophy; 4 Alain Eschalier and Christophe Mallet: The rediscovery of paracetamol; 5 Fabrizio Benedetti: The pharmacology of placebos; 6 Jean-Sebastien Walczak: Understanding the responsiveness of c-fibres; 7 Tony Dickenson: A new theory of pain; 8 Manon Choiniere and Gabriella Page: Three determinants of pain; 9 Guy Rousseau: Purinergic nerves: a new type of nerve; 10 Jeffrey S. Mogil: Genetic differences in opiate receptors; 11 Pierre Rainville: Endogenous opioids in placebo-induced analgesia; 12 Eric Troncy: Ethical pain experimentation in conscious animals; 13 Argyro Fassoulaki: Local anaesthetic creams; 14 Cathy Price: The backpain revolution; 15 Pierre Sirois and Pedro D’orleans-Juste: The mechanism of aspirin; 16 Yasser Al Omran and Qasim Aziz: Mechanisms of visceral pain in IBS; 17 Philippe Richebe and Cyril Rivat: The effects of morphine on the central nervous system; 18 Joan Hester: Opiods in palliative care; 19 Tony Dickenson: Endogenous opioids in the central nervous system; 20 Craig W. Steven: Spinal opioid analgesia in the rat; Section 2: Firsts; 21 Paul Farquhar-Smith: The key role of NGF in inflammatory pain processing; 22 Elizabeth J. Bradbury and Nicholas D. James: Mapping of neurotrophin receptors on adult sensory neurons; 23 Stephen R. Humble: Plasticity in somatic receptive fields after nerve injury; 24 Amanda Klein and Matthias Ringkamp: Peripheral neural mechanisms of cutaneous hyperalgesia and heat pain; 25 Mary E. Abood and Thomas Gamage: The Cloning and Characterization of CB1; 26 Mark F. Bird and David Lambert: Deorphanisation of ORL-1/LC132 by reverse pharmacology in two landmark studies; 27 Istvan Nagy: The capsaicin receptor; 28 Istvan Nagy: Vanilloid receptor 1 in inflammatory thermal hyperalgesia; 29 Pierre Rainville: A signature of pain in the brain; 30 John Schutzer-Weissmann: Cytokines as central to peripheral sensitisation and hyperalgesia; 31 Claudia Sommer: Endogenous opioids mediate stress-induced analgesia; 32 Ke Ren Ronald Dubner: The first crystal structure of an iGluR ligand-binding core; 33 Andrea Hohmann: Control of pain initiation by endogenous cannabinoids; 34 Julie Desroches: Peripheral Analgesia involves Cannabinoid Receptors; 35 Marzia Malcangio: Glia: a new pain target; 36 Bradley Kerr and Muhammad Saad Yousuf: The challenges of animal models of pain; 37 Philippe Sarret: Mechanisms of bone cancer pain; 38 Roger Knaggs: Molecular Structure of the Mu-Opioid Receptor; 39 Serge Marchand: Milestone Effect of DNIC in our Understanding of Pain; 40 Sheila Black: Original description of central sensitisation; 41 Lesley Bromley: Molecular basis for Placebo effect; Section 3: Science; 42 Robert D. Searle: Early discussions on a mechanistic approach to pain; 43 Alfredo Ribeiro and Da Silva Claire Magnussen: Plasticity: a key concept in pain; 44 Enrique Collantes: The importance of descending modulatory pain systems; 45 Helen Laycock: Nocebo and its importance in clinical practice; 46 Pierre Beaulieu: Mechanisms of Action of Acetaminophen for Pain Treatment; 47 Juergen Sandkuehler: Making the link from central sensitization to clinical pain; Section 4: Clinical; 48 Vicky Tidman: Proof of concept: epidural morphine; 49 Mike Shipley: The Definition of Fibromyalgia; 50 Suzanne Chapman: The advent of PCA for post operative analgesia; 51 Matthew J. Allsop and Michael Bennett: Undertreatment of pain with metastatic cancer; 52 Alison Bliss: Faces scales in paediatric pain assessment; 53 Stephan Schug: Epidural block and phantom limb pain; 54 Giovambattista Zeppetella: Clarifying the concept of Breakthrough pain; Section 5: Mechanisms; 55 Alison Bliss: Paediatric pain epidemiology; 56 Peter Kamerman: Recognising the importance of HIV disease and pain; 57 Andrew N. Davies: Fast acting fentanyl for breakthrough pain; 58 Paul Farquhar-Smith: The additive analgesia of adrenaline in epidural blockade; 59 Felicia Cox: What is the clinical relevance of the Likert scale for pain; 60 Jane Quinlan: Post operative pain: assessing the standards; 61 Kirsty Bannister: Opioid induced hyperalgesia; 62 Naomi Scott: CRPS epidemiology; 63 Paul Farquhar-Smith: Seminal paper on epidemiology of cancer pain; 64 Arun Bhaskar: Endoscopic ultrasound guided coeliac plexus block; Section 6: Neuropathic; 65 Nicholas D. James and Elizabeth J. Bradbury: Autotomy: an early neuropathic pain model; 66 Tudor Phillips: Risk factors for post amputation pain; 67 Matthew Brown: Chronic constriction injury (CCI) model of neuropathic pain; 68 Mick G. Serpell: Antineuropathic medication combination therapy; 69 Rajesh Gupta: RCT evidence for gabapentin in post herpetic neuralgia; 70 Turo J. Nurmikko: Identification of the target of gabapentinoid action in neuropathic pain; 71 Matthew Brown: Recognition of the importance of Neuropathic pain epidemiology; 72 Abdelghani Mowafak: Botox analgesia for neuropathic pain; 73 Sibtain Anwar: DNIC and prediction of chronic post surgical pain; 74 Richard M. Langford: Pregabalin in the reduction of chronic post knee surgery chronic pain; 75 Toby Newton John: Multidisciplinary Cognitive Behavioural Treatment for Chronic Pain; 76 Rakesh Jain: Disability in Chronic Low Back Pain; Section 7: Psychosocial; 77 Amanda Williams: The Understanding of Social Effects in Pain; Section 8: Genetics; 78 Bhagat Singh. Alban Latremoliere, and Michael Costigan: Congenital insensitivity to pain; 79 Ingolf Cascorbi: Polymorphic CYP2D6 as the Responsible Enzyme of Activation; 80 Matthew Hamilton: COMT genotypes in pain responses; 81 Bradley J. Kerr: The link between NaV1.7 mutation and erythromelalgia; 82 Fausto Morell-Ducos: COMT and morphine use in cancer pain; 83 Roman Cregg and Biloshytsky Vadym: Pioneering use of gene therapy for pain

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