图书简介

Preface; Acknowledgments; 1. Seduced by Drug Discovery; 2. Proscar and Propecia: the Gary and Jerry Show; 3. Basic research, snake venoms and ACE inhibitors: Ondetti, Cushman and Patchett; 4. HIV protease inhibitors: weapons in the way against HIV/AIDS; 5. Statins: protection against heart attacks and strokes - Hallelujah; 6. The perils of Primaxin; 7. The discovery of taxol: Wall, Horwitz, Holton; 8. Avermectins: molecules of life battle parasites; 9. Fludalanine: nice try but no cigar; 10. Diabetes breakthroughs: Thornberry and Weber; 11. Take it off! Take it all off! Drugs for weight reduction; 12. The conquest of hepatitis C: telaprevir and beyond; Appendix A: The small molecules of life: some basics of chemistry; Appendix B: The basics of protein structure; Appendix C: Proteins perform multiple functions: enzymes, receptors, ion channels; Appendix D: The basics of drug discovery and development; Appendix E: Structures of key molecules

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