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Section I: Fundamentals of Critical Care; 1. Respiratory Physiology in Critical Illness; Minkyung Kwon, MD and Jose L. Diaz-Gomez, MD; 2. Mechanical Ventilation: Basic Modes; Amelia A. Lowell, RRT, RCP; 3. Mechanical Ventilation: Advanced Modes; Amelia A. Lowell, RRT, RCP and Bhavesh M. Patel, MD; 4. Cardiovascular System in the Critically Ill Patient; Juan G. Ripoll Sanz, MD; Norlalak Jiramethee, MD; and Jose L. Diaz-Gomez, MD; 5. Renal Function in Critically Ill Patients; Pramod K. Guru, MBBS, MD; 6. Nutrition in Critical Illness; Angela N. Vizzini, RDN, LD/N and Mireille H. Hamdan, RDN, LD/N; Section I: Questions and Answers; Section II: Fundamentals of Neurocritical Care; 7. Neurologic Examination in Neurocritical Illness; Eelco F. M. Wijdicks, MD, PhD; 8. Intracranial Pressure; Eelco F. M. Wijdicks, MD, PhD and William D. Freeman, MD; 9. Cerebrospinal Physiology; Joseph Zachariah, MD; 10. Cerebral Circulation and Cerebral Blood Flow; Arnoley S. Abcejo, MD and Jeffrey J. Pasternak, MD; 11. Consequences of Anoxia and Ischemia to the Brain; Jennifer E. Fugate, DO; 12. Consequences of Acute Metabolic Changes to the Brain; Sherri A. Braksick, MD and Sara E. Hocker, MD; 13. Consequences of Acute Hypertension to the Brain; Katherine M. Oshel, MD and Hani M. Wadei, MD; 14. Coma and Other Altered States of Consciousness; Eelco F. M. Wijdicks, MD, PhD; 15. Neuromuscular Respiratory Failure; Maximiliano A. Hawkes, MD and Eelco F. M. Wijdicks, MD, PhD; 16. Neurogenic Breathing Patterns; Eelco F. M. Wijdicks, MD, PhD; 17. Neurogenic Cardiac Manifestations; Sherri A. Braksick, MD and Eelco F. M. Wijdicks, MD, PhD; 18. Paroxysmal Sympathetic Hyperactivity; Kevin T. Gobeske, MD, PhD; Section II: Questions and Answers; Section III: Critical Care Disorders; Pulmonary Disorders; 19. Acute Respiratory Distress Syndrome; Richard K. Patch III, MD and James Y. Findlay, MB, ChB; 20. Pulmonary Embolism: An Overview; Brandon T. Nokes, MD and Rodrigo Cartin-Ceba, MD; 21. Asthma in the Critically Ill Patient; Jonathan J. Danaraj, DO and Augustine S. Lee, MD; 22. Chronic Obstructive Pulmonary Disease Exacerbation; Isabel Mira-Avendano, MD and Minkyung Kwon, MD; 23. Pleural Diseases in Critical Care Medicine; Karthika R. Linga, MBBS and Neal M. Patel, MD; 24. Pulmonary Malignancy; Ali A. Zaied, MD and Margaret M. Johnson, MD; 25. Pulmonary Hypertension and Right-Sided Heart Failure in the Critically Ill; Charles D. Burger, MD; Cardiovascular Disorders; 26. Anaphylaxis and Anaphylactic Shock; Megan S. Motosue, MD and Gerald W. Volcheck, MD; 27. Cardiogenic Shock; Robert A. Ratzlaff, DO and Jason L. Siegel, MD; 28. Acute Coronary Syndrome; Siva S. Ketha, MD and Juan Carlos Leoni Moreno, MD; 29. Cardiac Rhythm and Conduction Disturbances; Yahaira Ortiz Gonzalez, MD and Fred Kusumoto, MD; 30. Hypertensive Emergencies; Denzil R. Hill, MD and James A. Onigkeit, MD; 31. Cardiopulmonary Resuscitation; Richard K. Patch III, MD; 32. Vascular Emergencies of the Aorta; Tariq Almerey, MD; January F. Moore; and Houssam Farres, MD; Acute Endocrine Disorders; 33. Pituitary Apoplexy; Sherri A. Braksick, MD; 34. Diabetes Insipidus; Dana Erickson, MD; 35. Panhypopituitarism; Diane Donegan, MB, BCh and Irina Bancos, MD; 36. Thyroid Disorders in the Intensive Care Unit; John E. Moss, MD; 37. Glycemic Control in Neurocritically Ill Patients; Carla P. Venegas-Borsellino, MD; Michael A. Pizzi, DO, PhD; and Santiago Naranjo-Sierra, MD; 38. Adrenal Insufficiency in Neurocritically Ill Patients; Carla P. Venegas-Borsellino, MD and Santiago Naranjo-Sierra, MD; Gastrointestinal Disorders; 39. Acute Gastrointestinal Hemorrhage; Pablo Moreno Franco, MD and Philip E. Lowman, MD; 40. Paralytic and Obstructive Ileus; Juan M. Canabal, MD; 41. Acute Liver Failure; James Y. Findlay, MB, ChB; 42. Acute Perforations of the Gastrointestinal Tract; Levan Tsamalaidze, MD and John A. Stauffer, MD; 43. Acute Vascular Disorders of the Intestine; Omar Y. Mousa, MBBS and Surakit Pungpapong, MD; 44. Abdominal Compartment Syndrome; Daniel J. Johnson, MD; Renal Disorders; 45. Acute Kidney Injury; Ankit Sakhuja, MBBS and Kianoush B. Kashani, MD; 46. Acid-Base Disorders; Onur Demirci, MD; 47. Drug Dosing in Renal Failure; Daniel A. Jackson, PharmD, RPh; 48. Principles of Renal Replacement Therapies; Peter M. Fitzpatrick, MD; 49. Disorders of Water and Electrolyte Balance; Yuzana Zaw, MBBS and Mira T. Keddis, MD; Hematologic and Inflammatory Disorders; 50. Anemia and Blood Transfusion; Joy D. Hughes, MD; Mariela Rivera, MD; and Myung S. Park, MD, MS; 51. Hematologic and Oncologic Complications in the Intensive Care Unit; Carl A. Ruthman, MD and Jose C. Yataco, MD; 52. Thrombocytopenia and Thrombocytopathy; Gretchen Johns, MD; 53. Disseminated Intravascular Coagulation: Clinical Diagnosis and Management; Prakash Vishnu, MBBS and Sikander Ailawadhi, MD; 54. Diagnosis and Management of Acquired Bleeding Disorders; Rajiv K. Pruthi, MBBS; 55. Anticoagulation Monitoring and Reversal; Theresa N. Kinard, MD; 56. Therapeutic Plasma Exchange for Acute Hematologic Disorders; Jill Adamski, MD, PhD; 57. Rheumatologic and Autoimmune Emergencies; Megan L. Krause, MD and Kevin G. Moder, MD; Sepsis and Other Infectious Diseases; 58. Infectious Diseases Complicating Critical Care; David A. Sotello Aviles, MD and Walter C. Hellinger, MD; 59. Antibiotics in the Intensive Care Unit; David A. Sotello Aviles, MD and Walter C. Hellinger, MD; 60. Sepsis and Septic Shock; Charles R. Sims III, MD and Thomas B. Comfere, MD; Dermatologic Concerns; 61. Dermatologic Emergencies in the Intensive Care Unit; Matthew R. Hall, MD; Trauma and Burns; 62. Initial Approach to the Management of Multisystem Trauma; David S. Morris, MD; 63. Chest and Abdominal Trauma; Joy D. Hughes, MD and David S. Morris, MD; 64. Skeletal Trauma; Joshua S. Bingham, MD and Kevin J. Renfree, MD; 65. Burns and Electrical Injuries; Brandon T. Nokes, MD and Ayan Sen, MD; Cardiothoracic Critical Care; 66. Cardiothoracic Surgery and Postoperative Intensive Care; Juan G. Ripoll Sanz, MD and Robert A. Ratzlaff, DO; 67. Mechanical Circulatory Assist Devices; Ayan Sen, MD and Bhavesh M. Patel, MD; 68. Extracorporeal Membrane Oxygenation; J. Kyle Bohman, MD and Gregory J. Schears, MD; 69. Cardiac Pacing in the Intensive Care Unit; J. William Schleifer, MD; Farouk Mookadam, MB, BCh; and Harish Ramakrishna, MD; Transplant Critical Care; 70. Clinical Management of Heart Transplant Recipients; Arzoo Sadiqi, BS and Jama Jahanyar, MD, PhD; 71. Critical Care of Heart-Lung and Lung Transplant Recipients; Ramachandra R. Sista, MD; 72. Clinical Management of Liver Transplant Recipients; Bhargavi Gali, MD; 73. Clinical Management of Kidney Transplant Recipients; James A. Onigkeit, MD; 74. Small Intestinal Transplant; Ayan Sen, MD; Toxicity and Toxins; 75. Serotonin Syndrome; Kevin T. Gobeske, MD, PhD and Eelco F. M. Wijdicks, MD, PhD; 76. Neuroleptic Malignant Syndrome and Hyperthermia; J. Ross Renew, MD and Monica Mordecai, MD; 77. Clinical Toxicology: Selected Drugs of Abuse and Chemical and Biological Warfare Agents; Matthew D. Sztajnkrycer, MD, PhD; Section III: Questions and Answers; Section IV: Neurocritical Illness; Acute Cerebrovascular Disorders; 78. Diagnosis and Management of Hemispheric Infarction; Sanjeet S. Grewal, MD and Benjamin L. Brown, MD; 79. Basilar Artery Occlusion; Michael R. Pichler, MD and Jennifer E. Fugate, DO; 80. Carotid Artery Disease; Nnenna Mbabuike MD and Rabih G. Tawk, MD; 81. Adult Primary Central Nervous System Vasculitis; Carlo Salvarani, MD; Robert D. Brown Jr, MD, MPH; and Gene G. Hunder, MD; 82. Intracerebral and Intraventricular Hemorrhage; Oana Dumitrascu, MD and Maria I. Aguilar, MD; 83. Subarachnoid Hemorrhage; Giuseppe Lanzino, MD and Biagia La Pira, MD; 84. Intracranial Arteriovenous Malformations; Kelly D. Flemming, MD and Michael J. Link, MD; 85. Cerebral Venous and Dural Sinus Thrombosis; Sara E. Hocker, MD; 86. Cervical Arterial Dissection; Bart M. Demaerschalk, MD; Traumatic Brain and Spine Injury; 87. Traumatic Brain and Spinal Cord Injury; Maya Babu, MD; 88. Traumatic Epidural and Subdural Hematomas; Patrick R. Maloney, MD and Michelle J. Clarke, MD; 89. Unstable Spinal Fractures; William E. Clifton III, MD and Mark A. Pichelmann, MD; Acute Central Nervous System Infections; 90. Encephalitis; Allen J. Aksamit Jr, MD; 91. Acute Bacterial Meningitis; Eelco F. M. Wijdicks, MD, PhD; 92. Brain Abscess and Spinal Epidural Abscess; Selby G. Chen, MD; Acute Neuromuscular Disorders; 93. Myasthenia Gravis; Maximiliano A. Hawkes, MD and Eelco F. M. Wijdicks, MD, PhD; 94. Guillain-Barre Syndrome; Eelco F. M. Wijdicks, MD, PhD; 95. Amyotrophic Lateral Sclerosis; Jennifer M. Martinez-Thompson, MD and Nathan P. Staff, MD, PhD; 96. Rhabdomyolysis and Toxic Myopathies; Justin C. Kao, MB, ChB and Margherita Milone, MD, PhD; 97. Myopathy and Neuropathy Acquired in the Intensive Care Unit; Priya S. Dhawan, MD and Jennifer A. Tracy, MD; Miscellaneous Disorders of Acute Brain Injury; 98. Status Epilepticus; Christopher P. Robinson, DO, MS and Sara E. Hocker, MD; 99. Posterior Reversible Encephalopathy Syndrome; Sudhir V. Datar, MBBS and Jennifer E. Fugate, DO; 100. Demyelinating Disorders of the Central Nervous System; Aurelia A. Smith, MD and Brian G. Weinshenker, MD; 101. Rapidly Progressive Dementia and Coma; Prasuna Kamireddi, MBBS; Jason L. Siegel, MD; and Dennis W. Dickson, MD; Neuro-oncology; 102. Brain and Spine Tumors; Mithun Sattur, MBBS; Matthew E. Welz, MS; and Bernard R. Bendok, MD; 103. Neoplastic Meningitis; Alyx B. Porter, MD; 104. Autoimmune Encephalitis; Eslam Shosha, MB, BCh and Sean J. Pittock, MD; 105. Radiation Therapy; Sameer R. Keole, MD; Postoperative Neurosurgery; 106. Intensive Care After Spinal Surgery; Clarence B. Watridge, MD; 107. Intensive Care After Craniotomy; Kelly Gassie, MD; Belinda G. Bradley, APRN; Robert E. Wharen Jr, MD; and Betty Y. S. Kim, MD, PhD; 108. Intensive Care After Neuroendovascular Procedures; Mithun Sattur, MBBS; Chandan Krishna, MD; Bernard R. Bendok, MD; and Brian W. Chong, MD; Section IV: Questions and Answers; Section V: Imaging in Critical Illness; 109. Radiography and Computed Tomography of the Chest; Barbara L. McComb, MD; 110. Abdominal Radiography; Joseph G. Cernigliaro, MD; 111. Fluoroscopy: Principles and Safety; David M. Sella, MD; Glenn M. Sturchio, PhD; and Beth A. Schueler, PhD; 112. Ultrasonography; Santiago Naranjo-Sierra, MD and Lauren K. Ng Tucker, MD; 113. Transesophageal Echocardiography; Ryan C. Craner, MD; Farouk Mookadam, MB, BCh; and Harish Ramakrishna, MD; Section V: Questions and Answers; Section VI: Procedures; Airway Procedures and Modes of Ventilation; 114. Basics of Airway and Oxygen Delivery Devices; Andrew W. Murray, MD; 115. Endotracheal Intubation Procedures; Matthew J. Ritter, MD; 116. Noninvasive Positive Pressure Ventilation; Karen W. Hampton, MS, RRT; 117. Tracheostomy; Saba Ghorab, MD and David G. Lott, MD; 118. Diagnostic and Interventional Bronchoscopy in the Intensive Care Unit; Cesar A. Keller, MD; Cardiovascular Cardiopulmonary Monitoring and Access; 119. Electrocardiographic Monitoring; Pragnesh P. Parikh, MD and K. L. Venkatachalam, MD; 120. Hemodynamic Monitoring; Hannelisa E. Callisen, PA-C; Stacy L. Libricz, PA-C, MS; and Ayan Sen, MD; 121. Pulmonary Artery Catheterization; Philip E. Lowman, MD; 122. Thoracentesis and Chest Tubes; Staci E. Beamer, MD; 123. Central Line Placement; Nicholas D. Will, MD and W. Brian Beam, MD; 124. Interventional Radiology Procedures; Rahmi Oklu, MD, PhD; Neuromonitoring and Procedures; 125. Intracranial Pressure Monitoring and External Ventricular Drainage; Maya Babu, MD and John L. D. Atkinson, MD; 126. Lumbar Puncture; Christina C. Smith, APRN; 127. Lumbar Drain; Jamie J. Van Gompel, MD; 128. Intraventricular Drug Administration; William W. Horn Jr, APRN and Benjamin L. Brown, MD; 129. Transcranial Doppler Ultrasonography; Mark N. Rubin, MD; 130. Electroencephalography; Amy Z. Crepeau, MD; 131. Essentials of Multimodal Brain Monitoring; Jennifer E. Fugate, DO; 132. Essentials of Cranial Neuroimaging; E. Paul Lindell, MD; Section VI: Questions and Answers; Section VII: Pharmacotherapeutics; 133. Anticonvulsant Drugs; Anteneh M. Feyissa, MD and Jeffrey W. Britton, MD; 134. Effects of Targeted Temperature Management on Drugs; Lauren K. Ng Tucker, MD; 135. Sedation and Analgesia; Juan G. Ripoll Sanz, MD and Jose L. Diaz-Gomez, MD; 136. Inotropes, Vasopressors, and Intravenous Antihypertensive Agents; Juan N. Pulido, MD; 137. Antibiotics, Antivirals, and Antifungals; David A. Sotello Aviles, MD and Walter C. Hellinger, MD; Section VII: Questions and Answers; Section VIII: Ethics in the Neurointensive Care Unit; 138. Palliative and End-of-Life Care in the Intensive Care Unit; Maisha T. Robinson, MD; 139. Communicating With Families; Cory Ingram, MD; 140. Brain Death; Eelco F. M. Wijdicks, MD, PhD; 141. Minimally Conscious State and Persistent Vegetative State; David T. Jones, MD; 142. Ethical Concerns and Care Before Organ Donation; Diane C. McLaughlin, APRN and Lauren K. Ng Tucker, MD; Section VIII: Questions and Answers; Index

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