COMPENDIUM OF IN VIVO MONITORING IN REAL-TIME MOLECULAR NEUROSCIENCE - VOLUME 2:MICRODIALYSIS AND SENSING OF NEURAL TISSUES
2
生物化学
￥
1859.00
售 价：
￥
1394.00
发货周期：预计3-5周发货
出版时间
2017年06月30日
装 帧
页 码
424
语 种
英文
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图书简介
Volume 1 of this series focused mainly on small molecules which are intrinsically electroactive. Volume 2 continues to provide current approaches to real time measurements of essential species in the central nervous system. It describes microdialysis, a sampling technique, which facilitates the removal of small volumes of solution containing the analyte(s) of interest which can be subsequently separated by chromatography and analyzed by a range of techniques. These include electrochemistry, UV-Vis spectroscopy, fluorescence and mass spectroscopy. This approach affords the opportunity to measure a range of targets in real-time thus providing access to pharmacokinetic/pharmacodynamics measurements affording the possibility of measuring the disappearance of a drug after administration and the subsequent appearance of metabolites. Microdialysis further affords the ability to sample peptides and proteins of neurobiological interest.
Consistent with the goals of Volume 1, Volume 2 seeks to provide for scientists in the field of neurobiology a base of bioanalytical techniques that may not be familiar to them. Specific examples are provided and the fundamental basis of the technique is also covered.
Key Feature:
o Excellent balance between the development and validation of methodology combined with investigators focused on detailed understanding of neurobiological processes
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