Neuromuscular Pathology Made Easy

Neuromuscular Pathology Made Easy

神经肌肉病理学变得容易
神经病学

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作者

Kurdi Maher

出版社

CRC Press

出版时间

2021年03月01日

装帧

平装

ＩＳＢＮ

9780367557263

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页码

240

开本

216x138 mm

语种

英文

综合评分

5 分

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The scope of Neuromuscular Pathology continuous to expand, as evidenced by the numerous multivolume and speciality texts published in recent years. This short textbook provides a complete overview of both clinical and histological aspects of common and rare neuromuscular diseases. The objective is twofold: to provide information about neuromuscular diseases in a simplified, integrated, and rapidly accessible format suited to those initially encountering the discipline, and also to provide a clear approach using simple pictures, tables and algorithms to illustrate histological features in muscle and nerve biopsy. This volume is conveniently divided into three sections with a total of 30 chapters. The first section deals with basic principles of neuromuscular histology and physiology, processing technique, histochemistry, and laboratory management. The second and third sections deal with neuromuscular diseases that are summarized in a stepwise approach, complemented by algorithms and organized tables.

A simplified, integrated, and rapidly accessible format covering both common and rare neuromuscular diseases

Clear simple illustrations, organized tables and algorithms to aid the reader in finding an easy approach to accurate diagnosis

Practical tips to facilitate histopathological diagnosis.

Clinical scenarios discussing common neuromuscular conditions Neurologists, neuropathologists, trainees and medical students involved in clinical neuroscience and pathology will find this guide of practical benefit in both education and practice.

Section A General Chapter 1: Muscle and Nerve Histology 1.1. Muscle histology 1.1.a Mitochondria 1.2. Peripheral nerve histology Chapter 2: Muscle and Nerve Fibers Classification 2.1. Muscle fiber classification 2.2. Peripheral nerve classification Chapter 3: Clinical Neurophysiology with Ahmed Abuzinadah 3.1. Nerve conduction study 3.2. Electromyography Chapter 4: Neuromuscular Laboratory Chapter 5: Chemical Materials Used in the Lab Chapter 6: Biopsy Processing Protocol with Habib Bin Attiah 6.1. Muscle 6.2. Nerve Chapter 7: Histochemistry Protocol with Fawaz Siddiq 7.1. Histochemical reaction 7.2. Histochemical methods 7.3. Immunohistochemistry 7.4. Histological artifacts Chapter 8: Genetic Basis with Ashraf Dallol 8.1. Single or multiple gene approach 8.2. Whole exam and genome sequencing 8.3. RNA sequencing Chapter 9: Neuromuscular Final Report 9.1. Muscle biopsy report template 9.2. Nerve biopsy report template Section B Muscle Chapter 10: Initial Approach in Muscle Biopsy 10.1. Myopathic features 10.2. Neuropathic features 10.3. Dystrophic features Chapter 11: Differential Diagnosis Chapter 12: Electron Microscopy Chapter 13: Classification of Myopathy Chapter 14: Approach to Neuromyopathy 14.1. Neuromyopathy with lack of inflammation 14.1.a. Paraneoplastic-induced neuromyopathy 14.1.b. Drug-induced neuromyopathy 14.2. Neuromyopathy with inflammation Chapter 15: Approach to Vacuolar Myopathy Chapter 16: Muscular Dystrophy Diseases Chapter 17: Inherited Myopathic Diseases Chapter 18: Non-Congenital Acquired Myopathies 18.1. Chronic diseases-induced myopathies 18.2. Toxic myopathies 18.2.a. Statin-induced myopathy 18.3. Critical care illness myopathy Chapter 19: Metabolic Myopathies 19.1. Glycogen storage diseases 19.1.a. POMPE disease 19.2. Lipid storage diseases 19.3. Mitochondrial myopathies 19.4. Other metabolic myopathies 19.4.a. Amyloid myopathy Chapter 20: Inflammatory Myopathies 20.1. Polymyositis 20.2. Dermatomyositis 20.3. Immune-Mediated Necrotizing Myopathies 20.4. Overlap myositis 20.5. Inclusion body myositis 20.6. Granulomatous myositis 20.7. Treated myositis in muscle biopsy Chapter 21: Chronic Denervation Myopathies with Ahmed Bamaga 21.1. Chronic denervation atrophy 21.2. Spinal muscular atrophy Chapter 22: Axial Myopathy Chapter 23: Fasciitis Section C Nerve Chapter 24: Classification of Neuropathy Chapter 25: Diagnostic Approach in Nerve Biopsy Chapter 26: Axonal Neuropathy Chapter 27: Demyelinating Neuropathy Chapter 28: Cellular and Extracellular Abnormalities Chapter 29: Inflammatory Demyelination 29.1. Acute Inflammatory Demyelinating Neuropathy 29.2. Chronic Inflammatory Demyelinating Neuropathy Chapter 30: Other Common Peripheral Neuropathies Appendix

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