图书简介

Preface; The Three-Dimensional Structure of Proteins; Chemical Catalysis; The Basic Equations of Enzyme Kinetics; Measurement and Magnitude of Individual Rate Constants; The pH Dependence of Enzyme Catalysis; Practical Methods for Kinetics and Equilibria; Detection of Intermediates in Enzymatic Reactions; Stereochemistry of Enzymatic Reactions; Active-Site-Directed and Enzyme-Activated Irreversible Inhibitors: \"Affinity Labels\" and \"Suicide Inhibitors\"; Conformational Change, Allosteric Regulation, Motors, and Work; Forces Between Molecules, and Binding Energies; Enzyme-Substrate Complementarity and the Use of Binding Energy in Catalysis; Specificity and Editing Mechanisms; Recombinant DNA Technology; Protein Engineering; Case Studies of Enzyme Structure and Mechanism; Protein Stability; Kinetics of Protein Folding; Folding Pathways and Energy Landscapes; Index;

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