Drug Efflux pumps in cancer resistance pathways:From molecular recognition and characterization to possible inhibition strategies in chemotherapy(Cancer Sensitizing Agents for Chemotherapy)

抗癌途径中的药物流出泵:从分子识别和表征到化疗中可能的抑制策略

工业经济学

售   价:
1436.00
发货周期:预计4-6周发货
作      者
出  版 社
出版时间
2019年11月01日
装      帧
精装
ISBN
9780128164341
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页      码
400
语      种
英文
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图书简介
Drug Efflux Pumps in Cancer Resistance Pathways: From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy, Volume Seven describes the fundamental aspects of efflux pumps of the ATP-binding cassette superfamily in cancer resistance pathways, along with strategies to target and improve chemotherapy efficacy. Pumps of the ATP-binding cassette superfamily (ABCs) regulate the access of drugs to the intracellular space. In this context, the overexpression of ABCs is a well-known mechanism of multidrug resistance in cancer and is associated with therapeutic failure. Cancer types discussed include breast, endocrine, hematologic, gastrointestinal, musculoskeletal, lung, skin and central nervous system cancers. The book is a valuable source for researchers and advanced students in cancer, biology, pharmacology, pharmaceutical sciences, biomaterials and medical/clinical sciences that are interested in accessing a comprehensive compendium on efflux pumps in mechanisms of cancer resistance.
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