Analyzing High-Dimensional Gene Expression and DNA Methylation Data with R(Chapman & Hall/CRC Computational Biology Series)
用R分析高维基因表达与DNA甲基化数据
生物工程This will be the first book to systematically describe the process and provide corresponding methods for analysing data generated from genetic- and epigenetic-studies. The overall subject is on large data analysis. Specifically, the book aims to provide a “pipe line” for genetic and epigenetic data analysis starting from raw genome- and epigenome-scale data. It includes methods to pre-process genetic and epigenetic data in the genome-scale, methods for data mining to identify potentially informative factors, and methods for subsequent analyses after data mining, e.g., factor/variable selections, network construction, and testing for differential networks.