图书简介
This book presents recent advances in the diagnosis, imaging, molecular pathogenesis, and therapy of myeloma in a single, practical volume. Different subtypes are discussed in comprehensive individual chapters, integrating etiology, pathogenesis, molecular pathology, histology, and therapy. Essential reading for any hematologist or oncologist treating patients with myeloma or related disorders.
馆藏图书馆
Harvard Library
Preface; Part I. Overview of Myeloma: 1. Epidemiology of myeloma Eve Roman and Alexandra G. Smith; 2. Diagnosis and immunophenotyping of myeloma Roger Owen; 3. Imaging of myeloma Nicola Mulholland and Ming Wan; Part II. Biological Basis for Targeted Therapies in Myeloma: 4. Cell cycle regulation and myeloma precursor cells John Quinn and Kwee L. Yong; 5. The genetic and epigenetic mechanisms underlying the behaviour of myeloma Martin F. Kaiser, Kevin D. Boyd and Gareth J. Morgan; 6. The myeloma bone marrow environment and survival signaling Kwee L. Yong, John Quinn and Asim Khwaja; 7. Immune dysfunction in multiple myeloma Guy Pratt and Paul Moss; 8. Myeloma bone disease: pathogenesis of bone destruction and therapeutic strategies Andrew Chantry and Neil Rabin; 9. Principles of pathway directed therapy for myeloma Yu-Tzu Tai and Kenneth C. Anderson; Part III. Myeloma: Clinical Entities: 10. Monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma Efstathios Kastritis and Meletios A. Dimopoulos; 11. Multiple myeloma: management of de novo disease T. Guglielmelli, P. Sonneveld, A. Broyl and Antonio Palumbo; 12. Treatment of relapsed/refractory myeloma Matthew J. Streetly, Jacob Laubach, Paul Richardson and Stephen A. Schey; 13. Solitary bone and extramedullary plasmacytoma Shirley D’Sa; 14. Amyloidosis Ashutosh D. Wechalekar, Simon W. Dubrey and Raymond L. Comenzo; 15. Waldenstrom’s macroglobulinemia/lymphoplasmocytic lymphoma Steven P. Treon and Giampaolo Merlini; 16. Castleman’s disease Karthik Ramasamy; 17. POEMS syndrome and paraproteinaemic syndromes: management and follow-up Angela Dispenzieri and Suzanne R. Hayman; Part IV. Supportive Therapies: 18. Treatment of emergent peripheral neuropathy and plasma cell disorders Charise Gleason, Melanie Watson and Sagar Lonial; 19. Management of renal failure in multiple myeloma Aneel Paulus, Pooja Advani, Nabeel Aslam and Asher Alban Chanan-Khan; 20. The management of infection in myeloma Christopher P. Conlon; Index.
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