Brain Targeted Drug Delivery Systems:A Focus on Nanotechnology and Nanoparticulates

图书简介

Brain Targeted Drug Delivery Systems: A Focus on Nanotechnology and Nanoparticulates provides a guide on nanoparticulates to both academic and industry researchers. The book discusses key points in the development of brain targeted drug delivery, summarizes available strategies, and considers the main problems and pitfalls evidenced in current studies on brain targeted drug delivery systems. As the brain is the most important organ in the human body, and disorders of the central nervous system (CNS) are the most serious threat to human life, this book highlights advances and new research in drug delivery methods to the brain.

1. Introduction and overview Part I Physiology and principles for brain targeting drug delivery 2. Anatomy and physiology of blood-brain barrier 3. Recent progress in blood-brain barrier transportation research 4. In vitro and in vivo models of BBB to evaluate brain targeting drug delivery Part II Nanoparticles-based brain targeting delivery strategies 5. Receptor-mediated transportation through BBB 6. Carrier-mediated transportation through BBB 7. Brain drug delivery by adsorption-mediated transcytosis 8. Efflux pump inhibition to enhance brain targeting delivery 9. Physically open BBB 10. Nanoparticle systems for nose-to-brain delivery 11. Brain local delivery strategy Part III Nanoparticles-based brain targeting delivery for CNS disorder management 12.Glioma targeted delivery systems 13.Nanotherapeutic strategies for the treatment of neurodegenerative diseases 14. Savaging brain ischemia by increasing brain uptake of neuroprotectants Part IV Perspective and pitfalls of nanoparticles-based brain targeting delivery 15. Neurotoxicity concern about the brain targeting delivery systems 16. The intra-brain distribution of brain targeting delivery systems 17. The elimination of brain-targeted nanomaterials 18. Perspective on brain targeting drug delivery systems

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Brain Targeted Drug Delivery Systems:A Focus on Nanotechnology and Nanoparticulates 脑靶向药物传递系统：关注纳米技术和纳米微粒 药理学

Brain Targeted Drug Delivery Systems:A Focus on Nanotechnology and Nanoparticulates

脑靶向药物传递系统：关注纳米技术和纳米微粒
药理学