Protein Carbonylation:Principles, Analysis, and Biological Implications(Wiley Series on Mass Spectrometry)

蛋白质羰基化:原理,分析和生物学意义

生物化学

售   价:
1580.00
发货周期:预计3-5周发货
作      者
出  版 社
出版时间
2017年05月26日
装      帧
精装
ISBN
9781119074915
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页      码
416
开      本
155.6x235mm
语      种
英文
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图书简介
Protein carbonylation has attracted the interest of a great number of laboratories since the pioneering studies at the Earl Stadtmans lab at NIH started in early 1980s. Since then, detecting protein carbonyls in oxidative stress situations became a highly efficient tool to uncover biomarkers of oxidative damage in normal and altered cell physiology. In this book, research groups from several areas of interest have contributed to update the knowledge regarding detection, analyses and identification of carbonylated proteins and the sites where these modifications occur. The scientific community will benefit from these reviews since they deal with specific, detailed technical approaches to study formation and detection of protein carbonyls. Moreover, the biological impact of such modifications in metabolic, physiologic and structural functions and, how these alterations can help understanding the downstream effects on cell function are discussed.
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