图书简介
This must-have practical manual in diagnostic histopathology and cytopathology enables practising pathologists and trainees to gain in-depth understanding of molecular techniques and explains how to incorporate them into routine diagnostic practice. A practical overview of current molecular techniques is followed by specialist chapters on specific molecular features in each system.
List of contributors; Preface; 1. An introduction to molecular pathology John M. S. Bartlett; 2. Molecular regulation of cellular function Marsela Braunstein and John M. S. Bartlett; 3. Practical application of molecular techniques in diagnostic histopathology and cytopathology and clinical management Abeer Shaaban and Fernando Schmitt; 4. Fluorescent and non-fluorescent in situ hybridization Jane Bayani and John M. S. Bartlett; 5. Clinical applications of the polymerase chain reaction for molecular pathology Angela B. Y. Hui, Annette D. Wong and Carlo V. Hojilla; 6. Are microarrays ready for prime time? Jane Bayani and John M. S. Bartlett; 7. Tissue microarrays Luigi Tornillo; 8. Sequencing Andrew M. K. Brown, Philipe C. Zuzarte and Paul M. Krzyzanowski; 9. Microsatellite instability in colorectal cancer Maria Sofia Fernandes, Raquel Seruca and Sérgia Velho; 10. Mutational analysis Aaron R. Hansen, Mahadeo A. Sukhai, Hal K. Berman, Suzanne Kamel-Reid and Philippe L. Bedard; 11. Tumors of the breast Cathy B. Moelans, Petra van der Groep, Robert Kornegoor, Jelle Wesseling and Paul J. van Diest; 12. Tumors of the female genital system Adhemar Longatto Filho, Sigurd F. Lax and Bin Yang; 13. Tumours of the male urogenital system Kirsten D. Mertz and Lukas Bubendorf; 14. Tumors of the gastrointestinal system Manuel Salto-Tellez, Benedict Yan, Roseann I. Wu and Martha Bishop Pitman; 15. Soft tissue, bone and skin tumours Stamatios Theocharis and Jerzy Klijanienko; 16. Cardio-thoracic tumors Umberto Malapelle, Claudio Bellevicine, Elena Vigliar and Giancarlo Troncone; 17. Tumors of the endocrine system Sylvia L. Asa and Ozgur Mete; 18. Haematological malignancies of the lymph nodes Sarah E. Coupland and Pedro Farinha; 19. Pediatric tumors Paul Roberts, Susan Picton and Jens Stahlschmidt; 20. Serous effusions Ben Davidson; 21. Academic applications and future of molecular pathology Manuel Salto-Tellez and Benedict Yan; Index.
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