Preparative Chromatography for Separation of Proteins(Wiley Series in Biotechnology and Bioengineering)

蛋白质分离的制备色谱法

军事医学

售   价:
1676.00
发货周期:预计3-5周发货
作      者
出  版 社
出版时间
2017年02月23日
装      帧
精装
ISBN
9781119031109
复制
页      码
608
开      本
155.6x235mm
语      种
英文
综合评分
暂无评分
我 要 买
- +
库存 50 本
  • 图书详情
  • 目次
  • 买家须知
  • 书评(0)
  • 权威书评(0)
图书简介
Preparative Chromatography for Separation of Proteins addresses a wide range of the most current modeling techniques, strategies, and case studies of industrial separation of proteins and peptides to aid in the efficiency and efficacy of this broadly-used technique in the purification of biopharmaceuticals. The chapters in the first section cover basic modeling and reviews, and focus on recent developments in chromatographic theory and research centered on facilitating a greater understanding of the fundamentals of chromatographic separation and behavior of proteins. Topics include thermodynamic approaches to mechanistic modeling and its uses (for example, in obtaining improved adsorption isotherms) and fundamental depictions of issues such as protein aggregation and its applications in modeling separation behavior. Chapters in the second section relate to industrial separations and case histories, addressing current and emerging trends in chromatographic unit operations and how mechanistic and empirical modeling approaches are utilized to optimize equipment and methodologies. Along with equipment such as column hardware, scale-down devices, and continuous operation mode, these chapters cover a variety of monitoring and control tools, including on-, in- and at-line equipment for improved process development and manufacturing methods, as well as presenting implementation and application of various modeling approaches--from multivariate data analysis and DoE to mechanistic modeling for establishment of chromatographic design space, on-column refolding and more. With its unique pairing of academic and industrial perspectives, Preparative Chromatography for Separation of Proteins is an indispensable resource for all those involved in the purification of biopharmaceuticals.
本书暂无推荐
本书暂无推荐
看了又看
  • 上一个
  • 下一个