DNA POLYMERASES:DISCOVERY, CHARACTERIZATION AND FUNCTIONS IN CELLULAR DNA TRANSACTIONS

DNA聚合酶:细胞DNA交换中的发现,特征和作用

细胞生物学

原   价:
1280.00
售   价:
960.00
发货周期:预计3-5周发货
作      者
出  版 社
出版时间
2010年04月15日
装      帧
精装
ISBN
9789814299169
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页      码
340
语      种
英文
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库存 30 本
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图书简介
Maintenance of the information embedded in the genomic DNA sequence is essential for life. DNA polymerases play pivotal roles in the complex physiological processes of DNA replication and repair. Besides the tasks in vivo, DNA polymerases are the workhorses in numerous biotechniques such as polymerase chain reaction (PCR), cDNA cloning, genome sequencing, nucleic acids–based diagnostics, as well as techniques to analyze ancient and otherwise damaged DNA. The authors have recently witnessed the discovery of a plethora of novel DNA polymerases with specialized properties whose physiological functions are only just beginning to be understood. This book summarizes the current knowledge of these fascinating enzymes in viruses, bacteria, archaea and eukaryotes. Moreover, some diseases are related to DNA polymerase defects, and chemotherapy through inhibition of DNA polymerases is used to fight HIV, Herpes, as well as Hepatitis B and C infections. This book will appeal to a broad audience including basic scientists, diagnostic laboratories, and clinicians who will gain an invaluable understanding of these fascinating enzymes. Key Features  Summarizes DNA polymerases in their physiological tasks as well as applications in modern chemistry, biology and medicine  Covers all aspects of prokaryotic and eukaryotic DNA polymerases  Appeals to a wide audience including students, academics, industry researchers, and medical professionals
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