Synthetic Peptides:A User’s Guide

图书简介

The first edition of this book sold about 2,500 copies in total, between Freeman, the original publisher, and Oxford. The field has become increasingly central to the strategies of pharmaceutical companies for drug design, and as a basic research tool for analyzing molecualr recognition and binding. This book provides the most generally useful and balanced treatment of a now-major but still cutting-edge field, with many practical suggestions and problem-solving hints for workers at the bench.

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Princeton University Library

1. Overview; Synthetic Peptides: Beginning the Twenty-first Century; References; 2. Peptide Design Considerations; Protein and Amino Acid Chemistry; Protein Structure; Application of Sequence Analysis to Modeling and Design; Design and Use of Combinational Peptide Libraries; Other Aspects of Peptide Design; Summary; References; 3. Principles and Practice of Solid-Phase Peptide Synthesis; Overview of Solid-Phase Strategy; Protection Schemes; Polymeric Support; Attachment to Support; Formation of Peptide Bond; Monitoring Automation of Solid-Phase Synthesis; Cleavage; Post-Translational Modifications and Unnatural Structures; Auxiliary Issues; Summary; Abbreviations; Acknowledgments; References; 4. Evaluation of the Synthetic Product; General Considerations; Purification; Detailed Characterization of Covalent Structure; Storage and Handling of Synthetic Peptides; How Much Is Enough; Acknowledgments; References; 5. Applications of Synthetic Peptides; Introduction; Structure/Function Studies; Systematic Modifications; Use of Peptides as Enzymatic Inhibitors and Therapeutic Agents; Receptor Studies - A Brief Overview of the Use of Peptides for Studies of Structure-Activity Relationships; The Use of Peptides for Affinity Labeling of Receptors; 6. Antigenic and Immunogenic Uses of Synthetic Peptides; Antisense Peptides; Summary and Future Perspectives; List of Abbreviations; Acknowledgements; References; Index

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Synthetic Peptides:A User’s Guide（Advances in Molecular Biology） 生物数学

Synthetic Peptides:A User’s Guide（Advances in Molecular Biology）
生物数学