Thymic Development and Selection of T Lymphocytes

T淋巴细胞的胸腺发展与选择

人体免疫学

原   价:
1105.00
售   价:
884.00
优惠
平台大促 低至8折优惠
出  版 社
出版时间
2013年11月15日
装      帧
精装
ISBN
9783642402517
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页      码
132
语      种
英语
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图书简介
The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place. Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.
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